Histrelin is a synthetic GnRH used to promote ovulation in horses. It possesses similar clinical efficacy in inducing ovulation in horses as deslorelin or hCG, but differs from the natural decapeptide GnRH in two amino acid substitutions.
Histrelin is an even more potent GnRH analogue than deslorelin, but with similar clinical efficacy in inducing ovulation in horses as deslorelin or hCG. Histrelin differs from the natural decapeptide GnRH in two amino acid substitutions.1
Results from studies suggested that 0.5 mg and 1 mg doses of histrelin resulted in ovulation in > 95% of estrus mares treated after follicle size and uterine edema scores met normal farm treatment parameters.2 Recently, a sustained-release (biorelease) formulation of histrelin was found to effectively induce ovulation within 2 days after administration.
Excepting very few examples of animals that proved to be allergic to histrelin, very few adverse effects have been reported. It is advised to call your veterinarian for medical advice about side effects regarding histrelin use in mares. In rare cases, irritation has been reported at injection sites 1. Once again, it is advisable to consult your veterinarian.
Contents: 0.5mg / mL, 10mL Bottle
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