Dosage and Administration See caution statement before applying. Apply directly on the lesion with a spatula or on a piece of gauze. The application of a bandage is optional. The preparation should be in contact with the lesion for at least 24 hours. The dressing may need to be changed several times a day or left on the lesion for a longer period of time. Caution: In case of deep or puncture wounds, or serious burns, consult a veterinarian. If redness, irritation, or swelling persists or increases, discontinue use and consult a veterinarian.